Anna Kendrick tries to get Joseph Gordon-Levitt to open up in this new still from their upcoming film, 50/50.

50/50 follows Adam (Levitt), a radio program writer who is diagnosed with a rare form of spinal cancer. With the help of his best friend (Seth Rogen), his mother (Anjelica Huston), and a young therapist (Kendrick) at the cancer center, Adam learns what and who the most important things in his life are.

WATCH THE TRAILER ON JUSTJARED

The movie opens on September 30th!