Sam Searches for a Cure for Dean on Tonight's All-New 'Supernatural'

Sam (Jared Padalecki) is on the hunt in this still from tonight’s Supernatural episode.

In “The Werther Project,” Sam learns that former Men of Letters, Magnus, once built a magical box and Sam sets out to find it in the hopes it can cure Dean (Jensen Ackles) of the Mark of Cain.

However, what he’s not prepared for is the deadly alarm system Magnus set up on the box.

When Sam opens the box, he puts both his and Dean’s life in danger.

Supernatural airs TONIGHT, April 22 @ 9PM on The CW!

15+ stills inside…